Antibacterial activity of human urine

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Antibacterial activity of human urine.

The fate of bacteria in human urine was studied after inoculation of small numbers of Escherichia coli and other bacterial strains commonly implicated in urinary tract infection. Urine from normal individuals was often inhibitory and sometimes bactericidal for growth of these organisms. Antibacterial activity of urine was not related to lack of nutrient material as addition of broth did not dec...

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Antibacterial activity of nifuratel in urine and serum.

The minimum inhibitory concentrations of nifuratel for 205 randomly selected isolates from urinary tract infections were tested by tube dilution. Of these, 177 (86.3%) were resistant to more than 6 mug/ml and 140 of 141 (99.3%) strains of Escherichia coli were resistant to more than 3 mug/ml. Urine levels of nifuratel were examined in two groups: one group had 400 mg given once and the other gr...

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Human Metabolome-derived Cofactors Are Required for the Antibacterial Activity of Siderocalin in Urine*

In human urinary tract infections, host cells release the antimicrobial protein siderocalin (SCN; also known as lipocalin-2, neutrophil gelatinase-associated lipocalin, or 24p3) into the urinary tract. By binding to ferric catechol complexes, SCN can sequester iron, a growth-limiting nutrient for most bacterial pathogens. Recent evidence links the antibacterial activity of SCN in human urine to...

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Antibacterial activity of human natural killer cells

The in vitro effects of human NK cells on viability of Gram-negative and Gram-positive bacteria was investigated. PBLs depleted of glass-adherent cells showed a significant antibacterial activity that was increased as the concentration of NK cells became higher. Leu-11-enriched cells exhibited the most efficient bactericidal activity. Stimulation of NK cells with staphylococcal enterotoxin B fo...

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Antibacterial activity of Fe3O4 nanoparticles

Antibacterial activity of Fe3O4 nanoparticles was investigated in three microorganisms including P. aeruginosa, E. Coli and Staphylococcus aureus. Fe3O4 nanoparticles were synthesized by chemical precipitation method (20 nm). The Fe3O4 nanoparticles antibacterial effect against Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus were studied by the culture method. First of all, e...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1968

ISSN: 0021-9738

DOI: 10.1172/jci105921